No More Wishing

With our Oxalate-Reducing Enzyme

There’s more on the table

Dietary restrictions, especially with oxalate-related nutritional limitations, can hold you back from enjoying a happy, healthy life. The first-known product of its kind, Nephure is an oxalate-reducing enzyme* allowing more freedom in your food choices.

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*Based on simulated stomach environment testing. 

What is Oxalate?

What is Oxalate?

Oxalate is found in plant-based foods, and is a so-called “anti-nutrient” because it binds with nutrients we need, like calcium and other minerals, making them less available for your body. Oxalate can be found in a wide array of foods especially leafy greens like spinach and kale, as well as potatoes, chocolate, grains, nuts, beans and more.

The Low-Oxalate Diet

The Low-Oxalate Diet

More and more people are recommended to follow a low-oxalate diet to help maintain a healthy calcium-oxalate ratio for kidney health. This means reducing or giving up foods full of oxalate – sometimes nutritious foods. This diet takes hard work and can be socially and emotionally restricting.

Nephure: The Oxalate-Reducing Enzyme

Enter Nephure:
The Oxalate-Reducing Enzyme

Nephure is a proprietary food ingredient that has been scientifically formulated, and lab tested, to reduce oxalate in foods and beverages.* It is inspired by an enzyme found in nature after years of scientific research. When used as directed, Nephure, provides more freedom in food choices, simplifying your low-oxalate diet and improving quality of life.

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Why Choose Nephure?

icon-usa Proudly made in the USA with carefully selected ingredients of international and domestic origin
icon-aua Nephure’s purpose is to assist you in limiting the intake of oxalate-dense foods as recommended by the AUA guidelines.**
icon-fda Manufactured in a Food and Drug Administration (FDA) registered facility complying with cGMP
icon-gluten Gluten Free
icon-lab Lab Tested

Product is lab tested to assure accuracy and quality
icon-sodium Sodium Free
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**AUA Guidelines on the Dietary Management of Kidney Stones (Diet Therapies #10)

Visit Our Low-Oxalate Community Resource Center

We believe that oxalate education is important, not only for people who are actively working to maintain kidney health, but also for people who hope to become more health conscious and informed about the food we eat.

What do Nephure Customers Have to Say?


"I do fairly routine 24 hour urine analysis to monitor my kidney function.  My average oxalate level tends to be around 58mg / day. This last time, starting 48 hours before my test, I took two packets of Nephure per day following the directions on the packets.  With no other dietary changes, my oxalate level was 32mg / day.  It's never been that low before. My doctor suggested that my diet has improved. Prayers for continued success -- the world needs your product!  Thanks!!!"  - Jim


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The Nephure Low-Oxalate Shop: Because food is life Scale down the hard work of  a low-oxalate diet and enjoy some of the foods you love during family mealtime  with less hassle. Visit the Nephure Low-Oxalate Shop, and experience how to  make your kidney health program easier. Shop Now ›